Regucalcin Expression in Bovine Tissues and Its Regulation by Sex Steroid Hormones in Accessory Sex Glands

Regucalcin Expression in Bovine Tissues and Its Regulation by Sex Steroid Hormones in Accessory Sex Glands

Regucalcin (RGN) is a mammalian Ca2+-binding protein that plays an important role in intracellular Ca2+ homeostasis. Recently, RGN has been identified as a target gene for sex steroid hormones in the prostate glands and testis of rats and humans, but no studies have focused on RGN expression in bovine tissues. Thus, in the present study, we examined RGN mRNA and protein expression in the differ...

O-14: Effect of Kisspeptin on Testicular Tissue and Accessory Sex Glands, Seminal Vesicle and Prostate, in Prepubertal Rats

Background: Hypothalamus-derived kisspeptins are critical regulators of reproduction in nearly all mammalian species including the humans. These small peptides mediate their actions through the GnRH loop system. How kisspeptins regulate gonadal maturation in sexually immature male mammals remains elusive. To address this, kisspeptin was administered as subchronic (12 days) twice daily i. p. dos...

Tolnidamine-Induced Changes in the Testis, Sperm Count, Fertility and Accessory Sex Glands of the Laboratory Mouse

Background Tolnidamine-induced changes have been reported earlier on spermatogenesis, fertility and sperm count in rat, rabbit and langur monkey. The aim of this study is to assess the response of these aspects to tolnidamine in the laboratory mouse. MaterialsAndMethods Adult male mice (12-14 weeks old) of Parkes (P) strain were used in the present study. All the animals were divided into five ...

Regulation of mouse renal CYP2J5 expression by sex hormones.

Mouse CYP2J5 is abundant in kidney and active in the metabolism of arachidonic acid to epoxyeicosatrienoic acids. Western blots of microsomes prepared from mouse kidneys demonstrate that after puberty, CYP2J5 protein is present at higher levels in male mice than in female mice. Northern analysis reveals that CYP2J5 transcripts are more abundant in adult male versus female kidneys, indicating th...

Role of Hormones and Effects of Hormone Agonists on Development and Differentiation of Accessory Sex Glands